STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEA1Early endosome antigen 1. (1412 aa)    
Predicted Functional Partners:
RAB5C
RAB5C, member RAS oncogene family.
    
 0.941
RAB5B
RAB5B, member RAS oncogene family.
    
 0.941
LOC102366232
RAB5B, member RAS oncogene family.
    
 0.935
LAMP1
Lysosomal associated membrane protein 1.
      
 0.854
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
    
 
 0.740
RAB5A
RAB5A, member RAS oncogene family.
    
 0.719
LAMP2
Lysosomal associated membrane protein 2.
      
 0.713
LOC102354752
VPS9 domain-containing protein.
    
 0.686
RABGEF1
RAB guanine nucleotide exchange factor (GEF) 1.
    
 0.686
TLR9
Toll-like receptor 9.
    
 0.680
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.