Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
USP48Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1043 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.936
UBAC1
UBA domain containing 1.
    
   0.898
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.848
TRAF1
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.848
H3B7S8_LATCH
TNF receptor-associated factor.
    
 0.848
GLI1
GLI family zinc finger 1.
    
 
 0.751
MAX
MYC associated factor X.
    
 0.750
DYNC1LI1
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 
 0.749
UBA1
Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 
 0.723
UBA7
Uncharacterized protein; Belongs to the ubiquitin-activating E1 family.
   
 
 0.723
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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