Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC73Cell division cycle 73. (316 aa)    
Predicted Functional Partners:
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.999
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.999
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.999
CTR9
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.999
WDR61
WD_REPEATS_REGION domain-containing protein.
    
 0.993
H3AS02_LATCH
Uncharacterized protein.
    
 0.993
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.980
POLR2E
RNA polymerase II subunit E.
   
 0.980
POLR2H
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
 0.978
SUPT4H1
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.977
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.