STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPHX4Epoxide hydrolase 4. (367 aa)    
Predicted Functional Partners:
ECI2
Enoyl-CoA delta isomerase 2.
   
 0.619
TVP23A
Golgi apparatus membrane protein TVP23 homolog.
      
 0.535
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.533
COP1
COP1 E3 ubiquitin ligase.
      
 0.528
GSC
Goosecoid homeobox.
    
 
 0.494
AASDH
Aminoadipate-semialdehyde dehydrogenase.
    
 0.480
CACNA1I
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
   
  
 0.476
PXMP4
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.475
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
   
 
 0.475
KLHDC10
Kelch domain containing 10.
      
 0.469
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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