Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSPAN8Tetraspanin. (229 aa)    
Predicted Functional Partners:
PTPRC
Protein tyrosine phosphatase receptor type C.
     
 0.924
ZFC3H1
Zinc finger C3H1-type containing.
      
 0.813
SERGEF
Secretion regulating guanine nucleotide exchange factor.
      
 0.740
CPNE8
Copine 8.
      
 0.737
USH1C
USH1 protein network component harmonin.
   
 0.733
LOC102357427
Spermatogenesis associated 18.
      
 0.677
SYNGR3
Synaptogyrin.
     
 0.662
SYNGR2
Synaptogyrin.
     
 0.661
SYT13
Synaptotagmin 13.
     
 0.654
RRAD
RRAD, Ras related glycolysis inhibitor and calcium channel regulator.
     
 0.650
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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