STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSPAN8Tetraspanin. (229 aa)    
Predicted Functional Partners:
ZFC3H1
Zinc finger C3H1-type containing.
      
 0.796
CPNE8
Copine 8.
      
 0.772
SERGEF
Secretion regulating guanine nucleotide exchange factor.
      
 0.731
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
   
 0.727
USH1C
USH1 protein network component harmonin.
   
 0.725
PTPRC
Protein tyrosine phosphatase receptor type C.
     
 0.693
ILDR2
Immunoglobulin like domain containing receptor 2.
    
 
 0.684
ZNF536
Zinc finger protein 536.
      
 0.633
PKM
Pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.535
PTGFRN
Prostaglandin F2 receptor inhibitor.
    
 
 0.534
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.