STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISD1Zgc:110843. (108 aa)    
Predicted Functional Partners:
CISD3
Uncharacterized protein.
   
  
 0.738
DDB1
Damage specific DNA binding protein 1.
    
 
 0.680
DDA1
DET1 and DDB1 associated 1.
    
 
 0.628
TOMM70
Translocase of outer mitochondrial membrane 70.
      
 0.548
ATP5MG
ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...]
   
  
 0.509
UBQLN4
Ubiquilin 4.
      
 0.480
CARS2
Cysteinyl-tRNA synthetase 2, mitochondrial.
      
 0.470
ISCA2
Iron-sulfur cluster assembly 2.
    
 
 0.449
CCDC58
Coiled-coil domain containing 58.
   
  
 0.440
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
      
 0.420
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.