STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERBB3Protein kinase domain-containing protein. (1047 aa)    
Predicted Functional Partners:
SHC3
SHC adaptor protein 3.
    
 0.974
SHC1
SHC adaptor protein 1.
    
 0.974
LOC102351332
Zgc:158659; Belongs to the PI3/PI4-kinase family.
    
 0.971
NRG2
Neuregulin 2.
    
 0.971
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.971
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
 0.969
LOC102348007
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.966
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.966
SHC4
SHC adaptor protein 4.
    
 0.963
SHC2
SHC (Src homology 2 domain containing) transforming protein 2.
    
 0.959
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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