NFATC3 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NFATC3

Nuclear factor of activated T cells 3. (1027 aa)

Predicted Functional Partners:

MAPK10

0.978

MAPK8

0.978

PPP3CA

0.960

MAPK9

0.960

PPP3CC

0.960

NFATC2

0.643

H3A6A5_LATCH

0.617

H3AQR5_LATCH

0.617

FOSL1

0.586

SNX14

0.573

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOSL1	MAPK10	ENSLACP00000015752	ENSLACP00000010110	FOS like 1, AP-1 transcription factor subunit.	Mitogen-activated protein kinase 10.	0.483
FOSL1	MAPK8	ENSLACP00000015752	ENSLACP00000021152	FOS like 1, AP-1 transcription factor subunit.	Mitogen-activated protein kinase.	0.483
FOSL1	MAPK9	ENSLACP00000015752	ENSLACP00000002488	FOS like 1, AP-1 transcription factor subunit.	Mitogen-activated protein kinase.	0.483
FOSL1	NFATC3	ENSLACP00000015752	ENSLACP00000001488	FOS like 1, AP-1 transcription factor subunit.	Nuclear factor of activated T cells 3.	0.586
H3A6A5_LATCH	NFATC2	ENSLACP00000005176	ENSLACP00000022961	Serine/threonine-protein phosphatase.	Nuclear factor of activated T cells 2.	0.618
H3A6A5_LATCH	NFATC3	ENSLACP00000005176	ENSLACP00000001488	Serine/threonine-protein phosphatase.	Nuclear factor of activated T cells 3.	0.617
H3AQR5_LATCH	NFATC2	ENSLACP00000011986	ENSLACP00000022961	Serine/threonine-protein phosphatase.	Nuclear factor of activated T cells 2.	0.618
H3AQR5_LATCH	NFATC3	ENSLACP00000011986	ENSLACP00000001488	Serine/threonine-protein phosphatase.	Nuclear factor of activated T cells 3.	0.617
MAPK10	FOSL1	ENSLACP00000010110	ENSLACP00000015752	Mitogen-activated protein kinase 10.	FOS like 1, AP-1 transcription factor subunit.	0.483
MAPK10	MAPK8	ENSLACP00000010110	ENSLACP00000021152	Mitogen-activated protein kinase 10.	Mitogen-activated protein kinase.	0.900
MAPK10	MAPK9	ENSLACP00000010110	ENSLACP00000002488	Mitogen-activated protein kinase 10.	Mitogen-activated protein kinase.	0.994
MAPK10	NFATC2	ENSLACP00000010110	ENSLACP00000022961	Mitogen-activated protein kinase 10.	Nuclear factor of activated T cells 2.	0.454
MAPK10	NFATC3	ENSLACP00000010110	ENSLACP00000001488	Mitogen-activated protein kinase 10.	Nuclear factor of activated T cells 3.	0.978
MAPK8	FOSL1	ENSLACP00000021152	ENSLACP00000015752	Mitogen-activated protein kinase.	FOS like 1, AP-1 transcription factor subunit.	0.483
MAPK8	MAPK10	ENSLACP00000021152	ENSLACP00000010110	Mitogen-activated protein kinase.	Mitogen-activated protein kinase 10.	0.900
MAPK8	MAPK9	ENSLACP00000021152	ENSLACP00000002488	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.994
MAPK8	NFATC2	ENSLACP00000021152	ENSLACP00000022961	Mitogen-activated protein kinase.	Nuclear factor of activated T cells 2.	0.454
MAPK8	NFATC3	ENSLACP00000021152	ENSLACP00000001488	Mitogen-activated protein kinase.	Nuclear factor of activated T cells 3.	0.978
MAPK9	FOSL1	ENSLACP00000002488	ENSLACP00000015752	Mitogen-activated protein kinase.	FOS like 1, AP-1 transcription factor subunit.	0.483
MAPK9	MAPK10	ENSLACP00000002488	ENSLACP00000010110	Mitogen-activated protein kinase.	Mitogen-activated protein kinase 10.	0.994