Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NFATC3Nuclear factor of activated T cells 3. (1027 aa)    
Predicted Functional Partners:
MAPK8
Mitogen-activated protein kinase.
    
 0.974
PPP3CA
Serine/threonine-protein phosphatase.
    
 0.963
MAPK9
Mitogen-activated protein kinase.
    
 0.963
PPP3CC
Serine/threonine-protein phosphatase.
    
 0.963
S1PR1
Sphingosine-1-phosphate receptor 1.
     
  0.900
MAPK10
Mitogen-activated protein kinase 10.
    
 
 0.752
H3A6A5_LATCH
Serine/threonine-protein phosphatase.
    
 0.654
H3AQR5_LATCH
Serine/threonine-protein phosphatase.
    
 0.654
SNX14
Sorting nexin 14.
      
 0.653
PIK3AP1
Phosphoinositide-3-kinase adaptor protein 1.
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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