Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DHX57DExH-box helicase 57. (1371 aa)    
Predicted Functional Partners:
RPSA
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.
   
 
 0.858
LARP7
La ribonucleoprotein domain family member 7.
   
 
 0.815
MLST8
MTOR associated protein, LST8 homolog.
      
 0.807
ITSN2
Intersectin 2.
   
 0.780
CAPRIN1
Cell cycle associated protein 1.
   
 
 0.734
RPL3
Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.700
H3AJ45_LATCH
Uncharacterized protein.
    
  0.689
ITSN1
Intersectin 1 (SH3 domain protein).
    
  0.689
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.680
STXBP4
Syntaxin binding protein 4.
    
 0.655
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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