Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2ZVU1_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein. (227 aa)    
Predicted Functional Partners:
GNRH1
Gonadotropin releasing hormone 1.
     
 0.634
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.
      
 0.587
ESR2
Estrogen receptor 2.
     
 0.547
LOC102359416
Uncharacterized protein.
    
 0.535
GNA11
G protein subunit alpha 11.
    
 0.535
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor.
      
 0.506
PROK2
Prokineticin 2.
    
 0.470
DCN
Decorin; May affect the rate of fibrils formation.
      
 0.467
GHRL
Motilin_assoc domain-containing protein.
    
 0.462
CAPS2
Calcyphosine 2.
     
 0.456
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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