STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAMDC2MAM domain containing 2. (421 aa)    
Predicted Functional Partners:
LOC102356571
MAM domain-containing protein.
 
     
0.900
FAM163A
Family with sequence similarity 163 member A.
      
 0.699
PTPRM
Protein tyrosine phosphatase receptor type M.
    
 0.677
PCSK2
Proprotein convertase subtilisin/kexin type 2.
   
  
 0.637
NCAPD3
Cnd1 domain-containing protein.
      
 0.628
H3AFZ6_LATCH
Fraser extracellular matrix complex subunit 1.
     
 0.590
FRAS1
Uncharacterized protein.
     
 0.580
ANKRD66
Ankyrin repeat domain 66.
    
 0.555
CCBE1
Collagen and calcium binding EGF domains 1.
    
 
 0.549
PLA2G7
Platelet-activating factor acetylhydrolase.
      
 0.514
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.