VAV3 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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Experiments

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[Homology]

Score

VAV3

Si:ch73-383g2.1. (488 aa)

Predicted Functional Partners:

LOC102352006

0.972

RAC1

0.971

LOC102351732

0.958

RAC3

0.958

LOC102348007

0.938

PIK3R1

0.938

PIK3CB

0.932

PIK3CA

0.931

VAV1

0.900

LOC102366450

0.900

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102348007	LOC102351732	ENSLACP00000008684	ENSLACP00000006235	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Uncharacterized protein.	0.942
LOC102348007	LOC102352006	ENSLACP00000008684	ENSLACP00000023412	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Uncharacterized protein.	0.942
LOC102348007	LOC102366450	ENSLACP00000008684	ENSLACP00000013917	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Uncharacterized protein.	0.408
LOC102348007	PIK3CA	ENSLACP00000008684	ENSLACP00000017606	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.984
LOC102348007	PIK3CB	ENSLACP00000008684	ENSLACP00000014968	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.988
LOC102348007	PIK3R1	ENSLACP00000008684	ENSLACP00000015476	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Phosphoinositide-3-kinase regulatory subunit 1.	0.900
LOC102348007	RAC1	ENSLACP00000008684	ENSLACP00000015032	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Rac family small GTPase 1.	0.942
LOC102348007	RAC3	ENSLACP00000008684	ENSLACP00000022054	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Rac family small GTPase 3.	0.942
LOC102348007	VAV1	ENSLACP00000008684	ENSLACP00000012221	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Calponin-homology (CH) domain-containing protein.	0.937
LOC102348007	VAV3	ENSLACP00000008684	ENSLACP00000001525	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	Si:ch73-383g2.1.	0.938
LOC102351732	LOC102348007	ENSLACP00000006235	ENSLACP00000008684	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.942
LOC102351732	LOC102366450	ENSLACP00000006235	ENSLACP00000013917	Uncharacterized protein.	Uncharacterized protein.	0.601
LOC102351732	PIK3CA	ENSLACP00000006235	ENSLACP00000017606	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.955
LOC102351732	PIK3CB	ENSLACP00000006235	ENSLACP00000014968	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.970
LOC102351732	PIK3R1	ENSLACP00000006235	ENSLACP00000015476	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.942
LOC102351732	VAV1	ENSLACP00000006235	ENSLACP00000012221	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.968
LOC102351732	VAV3	ENSLACP00000006235	ENSLACP00000001525	Uncharacterized protein.	Si:ch73-383g2.1.	0.958
LOC102352006	LOC102348007	ENSLACP00000023412	ENSLACP00000008684	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.942
LOC102352006	LOC102366450	ENSLACP00000023412	ENSLACP00000013917	Uncharacterized protein.	Uncharacterized protein.	0.595
LOC102352006	PIK3CA	ENSLACP00000023412	ENSLACP00000017606	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.945