Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VAV3Si:ch73-383g2.1. (488 aa)    
Predicted Functional Partners:
LOC102352006
Uncharacterized protein.
   
 0.976
RAC1
Rac family small GTPase 1.
   
 0.973
LOC102351732
Uncharacterized protein.
   
 0.964
LOC102348007
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
  0.943
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
  0.943
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.
   
 
 0.941
LOC102351332
Zgc:158659; Belongs to the PI3/PI4-kinase family.
   
 
 0.934
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 
 0.934
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 
 0.934
SYK
Tyrosine-protein kinase.
   
 0.916
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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