STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCA4Chloride channel accessory 1. (866 aa)    
Predicted Functional Partners:
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
   
 
 0.740
WFS1
Wolframin ER transmembrane glycoprotein.
    
 0.678
COCH
Cochlin.
    
 0.662
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.652
CHIC2
Cysteine rich hydrophobic domain 2.
      
 0.641
SLC17A8
Solute carrier family 17 member 8.
      
 0.641
SLC26A5
Solute carrier family 26 member 5.
   
  
 0.628
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
   
 
  0.628
CWC25
CWC25 spliceosome associated protein homolog.
   
    0.607
MOCS3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
  0.607
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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