Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DLX2Distal-less homeobox 2. (278 aa)    
Predicted Functional Partners:
DLX5
Distal-less homeobox 5.
   
 
 0.983
DLX1
Distal-less homeobox 1.
   
 
 0.873
IRX1
Iroquois homeobox 1.
   
 
 0.784
TBR1
T-box brain transcription factor 1.
   
 
 0.782
FOXG1
Forkhead box G1.
   
 
 0.726
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
  
 0.687
DACT2
Dishevelled-binding antagonist of beta-catenin 2.
      
 0.683
GAD1
Glutamate decarboxylase 1.
   
  
 0.682
LHX6
LIM homeobox 6.
   
 
 0.676
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.651
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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