LOC102358920 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC102358920

Programmed cell death 4a. (244 aa)

Predicted Functional Partners:

TOPORS

0.661

FAF1

0.659

EIF4A1

0.610

LOC102345373

0.610

EIF4A2

0.610

EIF4A3

0.564

H3A592_LATCH

0.552

TET2

0.526

RECK

0.520

EIF3A

0.520

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF3A	EIF4A1	ENSLACP00000016956	ENSLACP00000003639	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 4A1A; Belongs to the DEAD box helicase family.	0.852
EIF3A	EIF4A2	ENSLACP00000016956	ENSLACP00000020272	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	0.852
EIF3A	LOC102345373	ENSLACP00000016956	ENSLACP00000005220	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.852
EIF3A	LOC102358920	ENSLACP00000016956	ENSLACP00000001540	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Programmed cell death 4a.	0.520
EIF4A1	EIF3A	ENSLACP00000003639	ENSLACP00000016956	Eukaryotic translation initiation factor 4A1A; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.852
EIF4A1	EIF4A3	ENSLACP00000003639	ENSLACP00000000123	Eukaryotic translation initiation factor 4A1A; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.906
EIF4A1	LOC102358920	ENSLACP00000003639	ENSLACP00000001540	Eukaryotic translation initiation factor 4A1A; Belongs to the DEAD box helicase family.	Programmed cell death 4a.	0.610
EIF4A2	EIF3A	ENSLACP00000020272	ENSLACP00000016956	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.852
EIF4A2	EIF4A3	ENSLACP00000020272	ENSLACP00000000123	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.906
EIF4A2	LOC102358920	ENSLACP00000020272	ENSLACP00000001540	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	Programmed cell death 4a.	0.610
EIF4A3	EIF4A1	ENSLACP00000000123	ENSLACP00000003639	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A1A; Belongs to the DEAD box helicase family.	0.906
EIF4A3	EIF4A2	ENSLACP00000000123	ENSLACP00000020272	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	0.906
EIF4A3	LOC102345373	ENSLACP00000000123	ENSLACP00000005220	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.906
EIF4A3	LOC102358920	ENSLACP00000000123	ENSLACP00000001540	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	Programmed cell death 4a.	0.564
FAF1	H3A592_LATCH	ENSLACP00000000178	ENSLACP00000004813	Fas associated factor 1.	Uncharacterized protein.	0.499
FAF1	LOC102358920	ENSLACP00000000178	ENSLACP00000001540	Fas associated factor 1.	Programmed cell death 4a.	0.659
H3A592_LATCH	FAF1	ENSLACP00000004813	ENSLACP00000000178	Uncharacterized protein.	Fas associated factor 1.	0.499
H3A592_LATCH	LOC102358920	ENSLACP00000004813	ENSLACP00000001540	Uncharacterized protein.	Programmed cell death 4a.	0.552
LOC102345373	EIF3A	ENSLACP00000005220	ENSLACP00000016956	Uncharacterized protein; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.852
LOC102345373	EIF4A3	ENSLACP00000005220	ENSLACP00000000123	Uncharacterized protein; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.906