Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2ZVX8_LATCHUncharacterized protein. (1434 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription.
    
 0.612
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
      
 0.610
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.609
IL10
Interleukin 10.
      
 0.595
CD68
Uncharacterized protein.
      
 0.594
VCL
Vinculin.
      
 0.592
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.592
BECN1
Beclin 1, autophagy related.
      
 0.591
MBP
Myelin basic protein.
      
 0.588
LOC102363280
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
      
 0.583
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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