STRINGSTRING
IRAK3 protein (Latimeria chalumnae) - STRING interaction network
"IRAK3" - Interleukin-1 receptor-associated kinase 3 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRAK3Interleukin-1 receptor-associated kinase 3 (546 aa)    
Predicted Functional Partners:
ACACA
acetyl-CoA carboxylase alpha (2312 aa)
     
  0.960
ACACB
acetyl-CoA carboxylase beta (2311 aa)
     
  0.960
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2 (1186 aa)
   
  0.932
LRRK2
Leucine-rich repeat kinase 2 (2508 aa)
   
  0.879
MYD88
Myeloid differentiation primary response 88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (286 aa)
     
  0.878
LRGUK
Leucine-rich repeats and guanylate kinase domain containing (595 aa)
   
  0.871
RIPK4
Receptor-interacting serine-threonine kinase 4 (566 aa)
     
  0.819
UBA52
Uncharacterized protein (128 aa)
       
  0.794
MIB1
Mindbomb E3 ubiquitin protein ligase 1 (989 aa)
     
  0.792
MIB2
Mindbomb E3 ubiquitin protein ligase 2 (942 aa)
     
  0.773
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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