Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCAF8SR-related CTD associated factor 8. (1071 aa)    
Predicted Functional Partners:
SCAF4
SR-related CTD associated factor 4.
   
  
 0.916
TMEM242
Transmembrane protein 242.
      
 0.888
SETX
Senataxin.
   
 
 0.875
DONSON
Downstream neighbor of SON.
      
 0.860
SERAC1
Serine active site containing 1.
      
 0.841
EXOSC10
Exosome component 10.
   
 
 0.833
PCF11
PCF11 cleavage and polyadenylation factor subunit.
   
 
 0.818
TULP4
TUB like protein 4.
      
 0.814
RPRD1B
Regulation of nuclear pre-mRNA domain containing 1B.
   
 
 0.790
DROSHA
Drosha ribonuclease III.
   
 
 0.787
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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