STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLIP3CAP-Gly domain containing linker protein 3. (536 aa)    
Predicted Functional Partners:
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.949
H3AF26_LATCH
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
      
 0.846
LOC102365523
Uncharacterized protein; Belongs to the peptidase C19 family.
    
  0.714
SUCLG2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.653
ZBTB7C
Zinc finger and BTB domain containing 7C.
    
 
 0.634
ZBTB7B
Zinc finger and BTB domain containing 7B.
    
 
 0.634
TTC38
Tetratricopeptide repeat domain 38.
      
 0.628
LOC102356355
TNFR-Cys domain-containing protein.
    
  0.619
RIPK1
Receptor interacting serine/threonine kinase 1.
    
  0.619
APLP1
Amyloid beta (A4) precursor-like protein 1.
   
  
 0.618
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (22%) [HD]