STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC102364679Centrin 4. (174 aa)    
Predicted Functional Partners:
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 0.994
UBE2V2-2
Ubiquitin-conjugating enzyme E2 variant 2.
   
 
 0.966
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 
 0.966
H3BBT7_LATCH
Uncharacterized protein.
    
 
 0.886
ENY2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
   
 
 0.874
PLK1
Serine/threonine-protein kinase PLK.
    
 0.869
AAMP
Angio associated migratory cell protein.
      
 0.860
PCID2
PCI domain containing 2.
    
 
 0.795
IFT88
Intraflagellar transport 88.
    
 0.786
DYNLL1
Dynein light chain.
   
 0.768
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.