STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (744 aa)    
Predicted Functional Partners:
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.743
GRIK5
Glutamate ionotropic receptor kainate type subunit 5.
  
 
0.696
GRIK4
Glutamate ionotropic receptor kainate type subunit 4.
  
 
0.694
H3BB64_LATCH
Uncharacterized protein.
 
  
 0.652
BPGM
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
      
 0.601
IGSF9B
Immunoglobulin superfamily member 9B.
      
 0.573
NETO2
Neuropilin and tolloid like 2.
   
 
 0.563
CNR1
Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family.
   
  
 0.546
MPDZ
Multiple PDZ domain crumbs cell polarity complex component.
    
 0.546
CDK5R1
Cyclin-dependent kinase 5 activator.
   
  
 0.537
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.