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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPP6R1Protein phosphatase 6 regulatory subunit 1. (724 aa)    
Predicted Functional Partners:
PPP6C
Serine/threonine-protein phosphatase.
    
 0.974
ANKRD28
Ankyrin repeat domain 28.
    
 0.898
ANKRD52
Ankyrin repeat domain 52.
    
 0.812
ANKRD66
Ankyrin repeat domain 66.
    
 0.706
ANKRD44
ANK_REP_REGION domain-containing protein.
    
 0.706
CEP170
Centrosomal protein 170.
    
 0.677
KSR1
Kinase suppressor of ras 1.
    
 
 0.672
PPP4C
Serine/threonine-protein phosphatase.
    
 0.661
LOC102350821
Serine/threonine-protein phosphatase.
   
 0.634
PPP2CA
Serine/threonine-protein phosphatase.
   
 0.634
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.