STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG1Pleckstrin homology and RhoGEF domain containing G1. (1193 aa)    
Predicted Functional Partners:
NOS1AP
Uncharacterized protein.
      
 0.702
GPR149
G protein-coupled receptor 149.
    
 
 0.695
LOC102350595
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
      
 0.636
CDC42
Cell division cycle 42.
    
 0.583
C1QTNF4
C1q and TNF related 4.
      
 0.575
KCNK1
Potassium channel subfamily K member.
      
 0.574
TNS4
Tensin 4.
      
 0.574
GULP1
GULP PTB domain containing engulfment adaptor 1.
      
 0.573
IYD
Iodotyrosine deiodinase.
      
 0.565
HS3ST1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.555
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.