Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (326 aa)    
Predicted Functional Partners:
LOC102359416
Uncharacterized protein.
    
 0.941
GNA11
G protein subunit alpha 11.
    
 0.941
SDHAF3
Succinate dehydrogenase complex assembly factor 3.
    
 0.705
POMC
Proopiomelanocortin.
      
 0.667
ITSN2
Intersectin 2.
     
  0.645
REPS1
RALBP1 associated Eps domain containing 1.
     
  0.574
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
     
  0.574
PROK2
Prokineticin 2.
     
 0.570
H3AJ45_LATCH
Uncharacterized protein.
     
  0.568
ITSN1
Intersectin 1 (SH3 domain protein).
     
  0.568
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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