Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily. (244 aa)    
Predicted Functional Partners:
PRL
Prolactin.
    
 0.971
H3ALZ2_LATCH
Uncharacterized protein.
    
 0.947
LOC102365044
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
 
     0.926
CLCF1
Cardiotrophin like cytokine factor 1.
    
 0.838
JAK2
Tyrosine-protein kinase.
    
 0.823
LOC102363504
Tyrosine-protein kinase.
    
 0.823
LOC102349296
Uncharacterized protein.
   
 0.754
H3B4D3_LATCH
Somatolactin alpha.
   
 0.754
H2ZYR6_LATCH
FERM domain-containing protein.
    
 0.708
LOC102356003
SH2 domain-containing protein.
    
 0.708
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (26%) [HD]