STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MLLT10MLLT10 histone lysine methyltransferase DOT1L cofactor. (835 aa)    
Predicted Functional Partners:
H2ZSI7_LATCH
PHD-type domain-containing protein.
 
      0.900
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 
 0.813
CARS1
Cysteinyl-tRNA synthetase.
    
   0.685
EEF1B2
Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family.
    
   0.652
VARS2
Uncharacterized protein.
    
   0.639
VARS1
Valyl-tRNA synthetase.
    
   0.639
CEBPG
CCAAT enhancer binding protein gamma.
    
   0.628
LOC102348026
Uncharacterized protein.
    
   0.563
LOC102358575
Uncharacterized protein.
    
   0.563
LOC106703183
C2H2-type domain-containing protein.
    
   0.559
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.