Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102362749Interfer-bind domain-containing protein. (265 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
    
 0.924
LOC102363504
Tyrosine-protein kinase.
    
 0.924
UQCRB
Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.
   
 0.922
CYC1
Cytochrome c1.
   
 0.922
IFNGR1
Uncharacterized protein.
   
 0.908
UQCRC2
Ubiquinol-cytochrome c reductase core protein 2.
   
 0.898
UQCRQ
Ubiquinol-cytochrome c reductase complex III subunit VII.
   
 0.885
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
 0.875
LOC102356003
SH2 domain-containing protein.
    
 0.843
JAK1
Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.843
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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