STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPPE1Metallophosphoesterase 1. (390 aa)    
Predicted Functional Partners:
PGAP3
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 
 0.772
CDC27
Cell division cycle 27.
      
 0.699
PIGB
Mannosyltransferase.
    
 
 0.694
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
    
 
 0.615
MRPL40
Mitochondrial ribosomal protein L40.
      
 0.601
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
      
 0.599
PIGH
Phosphatidylinositol glycan anchor biosynthesis class H.
    
 
 0.564
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
      
 0.552
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
      
 0.541
BATF3
Basic leucine zipper ATF-like transcription factor 3.
      
 0.537
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.