STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EN2Homeobox protein engrailed-like. (262 aa)    
Predicted Functional Partners:
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.584
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.500
PAX2
Paired box 2.
   
  
 0.484
TLE3
TLE family member 3, transcriptional corepressor.
    
 
 0.473
LOC102356408
Uncharacterized protein.
    
 
 0.473
LOC102356682
TLE family member 2, transcriptional corepressor b.
    
 
 0.473
TLE5
TLE family member 5, transcriptional modulator.
    
 
 0.473
TLE4
Uncharacterized protein.
    
 
 0.473
TLE1
Uncharacterized protein.
    
 
 0.473
PAX8
Paired box 8.
   
  
 0.447
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.