STRINGSTRING
EN2 protein (Latimeria chalumnae) - STRING interaction network
"EN2" - Engrailed homeobox 2 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EN2Engrailed homeobox 2 (262 aa)    
Predicted Functional Partners:
FGF8
Fibroblast growth factor 8 (androgen-induced) (213 aa)
     
   
  0.638
EGR2
Early growth response 2 (433 aa)
       
 
  0.606
NEURL
Neuralized homolog (Drosophila) (568 aa)
           
  0.589
NEURL1B
Neuralized homolog 1B (Drosophila) (534 aa)
           
  0.589
DHH
Desert hedgehog; Intercellular signal essential for a variety of patterning events during development (424 aa)
     
   
  0.580
SHH
Sonic hedgehog; Intercellular signal essential for a variety of patterning events during development (421 aa)
     
   
  0.580
IHH
Indian hedgehog; Intercellular signal essential for a variety of patterning events during development (410 aa)
     
   
  0.580
BMP4
Bone morphogenetic protein 4 (460 aa)
     
   
  0.566
CRX
Cone-rod homeobox (292 aa)
     
   
  0.564
TLE4
Transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) (734 aa)
       
 
  0.555
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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