STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCLCGlutamate-cysteine ligase catalytic subunit. (655 aa)    
Predicted Functional Partners:
GCLM
Glutamate-cysteine ligase modifier subunit.
   
 0.998
GSS
Glutathione synthetase.
   
 0.969
GSR
Glutathione reductase.
   
  
 0.754
LOC102345892
Zgc:110366.
   
 0.739
AKR1B1
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1.
   
 0.739
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 0.739
LOC102364057
Zgc:101765.
   
 0.739
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family.
   
 0.739
LOC102347995
Aldo_ket_red domain-containing protein.
   
 0.739
TCF19
Transcription factor 19.
   
 0.739
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.