Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
PPICPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (224 aa)    
Predicted Functional Partners:
SERPINH1
Serpin family H member 1; Belongs to the serpin family.
   
 0.893
RANBP1
RAN binding protein 1.
 
 
 0.893
FBN1
Fibrillin 1.
   
 0.813
P3H4
Prolyl 3-hydroxylase family member 4 (non-enzymatic).
   
 0.812
CRTAP
Cartilage associated protein.
   
 0.812
PRDX6
Peroxiredoxin 6.
   
 0.798
FBL
Fibrillarin.
   
 
 0.769
NCAN
Uncharacterized protein.
    
 0.742
CD248
CD248 molecule, endosialin a.
   
 0.732
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.721
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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