STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERAP1Aminopeptidase. (948 aa)    
Predicted Functional Partners:
TNKS2
Poly [ADP-ribose] polymerase.
   
 
 0.779
AGT
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.713
TAF2
TATA-box binding protein associated factor 2.
      
 0.609
TNKS
Poly [ADP-ribose] polymerase.
   
 
 0.564
TBC1D1
TBC1 domain family member 1.
     
 0.560
LOC102366063
PID domain-containing protein.
     
 0.560
REN
Renin; Belongs to the peptidase A1 family.
     
 0.560
TBC1D4
TBC1 domain family member 4.
     
 0.560
PREP
Prolyl endopeptidase.
  
  
 0.556
LOC102358151
Angiotensin-converting enzyme.
   
 
 0.545
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.