Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYNGR4MARVEL domain-containing protein. (141 aa)    
Predicted Functional Partners:
SCAMP1
Secretory carrier-associated membrane protein.
   
 
 0.572
TMC5
Transmembrane channel-like protein.
      
 0.468
TMC6
Transmembrane channel-like protein.
      
 0.468
LOC102346865
Threonine aldolase 1.
      
 0.467
AFMID
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
  
 0.462
ITSN2
Intersectin 2.
      
 0.454
H3AJ45_LATCH
Uncharacterized protein.
      
 0.452
ITSN1
Intersectin 1 (SH3 domain protein).
      
 0.452
PRPF38A
Pre-mRNA processing factor 38A.
   
  
 0.411
TK1
Thymidine kinase.
      
 0.400
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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