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MED23 protein (Latimeria chalumnae) - STRING interaction network
"MED23" - Mediator complex subunit 23 in Latimeria chalumnae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MED23Mediator complex subunit 23 (1277 aa)    
Predicted Functional Partners:
MED12
Mediator of RNA polymerase II transcription, subunit 12 homolog (2199 aa)
     
 
  0.925
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (1401 aa)
     
 
  0.916
MED18
Mediator complex subunit 18 (208 aa)
     
 
  0.903
MED28
Mediator complex subunit 28 (175 aa)
       
 
  0.901
ZC3H13
Zinc finger CCCH-type containing 13 (1785 aa)
     
      0.856
MED10
Mediator complex subunit 10 (135 aa)
     
 
  0.856
MED14
Mediator complex subunit 14 (1445 aa)
     
 
  0.855
MED7
Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery (235 aa)
     
 
  0.848
TRIP4
Thyroid hormone receptor interactor 4 (578 aa)
       
      0.848
OBFC1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication (372 aa)
       
      0.848
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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