STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZWC9_LATCHUncharacterized protein. (736 aa)    
Predicted Functional Partners:
RAB35
RAB35, member RAS oncogene family.
    
 
 0.701
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.566
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
 
 0.566
EXOC7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
     
 0.486
IFT27
Intraflagellar transport 27.
    
 
 0.478
RAB11FIP3
RAB11 family interacting protein 3.
    
 0.444
RAB11FIP4
RAB11 family interacting protein 4.
    
 0.433
EXOC5
Exocyst complex component 5.
   
 
 0.426
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.