STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP8AP2Caspase 8 associated protein 2. (1555 aa)    
Predicted Functional Partners:
LSM11
LSM11, U7 small nuclear RNA associated.
      
 0.607
NPAT
Nuclear protein, coactivator of histone transcription.
   
 
 0.581
LOC102350007
Small ubiquitin-related modifier.
    
  0.491
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
      
 0.485
PIAS4
Protein inhibitor of activated STAT 4.
    
  0.473
CBX4
Chromobox 4.
     
 0.465
CBX8
Chromobox 8.
     
 0.465
DSCC1
DNA replication and sister chromatid cohesion 1.
      
 0.455
GINS2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
      
 0.446
PRIM1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
  
 0.441
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.