Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HAS3Hyaluronan synthase 3. (550 aa)    
Predicted Functional Partners:
DELE1
Uncharacterized protein.
  
 0.687
CPVL
Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.
    
 
 0.670
HACL1
2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.
  
 0.603
ILVBL
IlvB acetolactate synthase like; Belongs to the TPP enzyme family.
  
 0.603
HECA
Hdc homolog, cell cycle regulator.
   
  
 0.596
GLA
Alpha-galactosidase.
      
 0.581
TNFAIP6
TNF alpha induced protein 6.
   
  
 0.570
LOC102354271
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.562
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.562
KDM6A
Lysine (K)-specific demethylase 6A.
  
 0.534
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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