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STRINGSTRING
IRF1 protein (Latimeria chalumnae) - STRING interaction network
"IRF1" - Interferon regulatory factor 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF1Interferon regulatory factor 1 (264 aa)    
Predicted Functional Partners:
STAT1
Signal transducer and activator of transcription 1, 91kDa (1179 aa)
     
 
  0.936
PSME2
Proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (241 aa)
     
   
  0.849
RSAD2
Radical S-adenosyl methionine domain containing 2 (360 aa)
     
   
  0.784
TLR3
Toll-like receptor 3 (766 aa)
     
   
  0.770
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (286 aa)
     
 
  0.744
STAT3
Signal transduction and activation of transcription 3 (763 aa)
     
 
  0.740
STAT2
Signal transducer and activator of transcription 2 (765 aa)
     
 
  0.739
IRF9
Interferon regulatory factor 9 (424 aa)
     
 
0.730
DDX58
DExD/H-box helicase 58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (944 aa)
     
   
  0.691
ISG15
ISG15 ubiquitin-like modifier (160 aa)
     
   
  0.684
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, Latimeria chalumnae, coelacanth
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