STRINGSTRING
IRF1 protein (Latimeria chalumnae) - STRING interaction network
"IRF1" - Interferon regulatory factor 1 in Latimeria chalumnae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF1Interferon regulatory factor 1 (264 aa)    
Predicted Functional Partners:
STAT1
Signal transducer and activator of transcription 1, 91kDa (1179 aa)
     
  0.726
STAT3
Signal transducer and activator of transcription 3 (acute-phase response factor) (763 aa)
     
  0.722
STAT2
Signal transducer and activator of transcription 2, 113kDa (765 aa)
     
  0.675
SOCS1
Suppressor of cytokine signaling 1 (190 aa)
     
 
  0.614
MYD88
Myeloid differentiation primary response 88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (286 aa)
     
 
  0.603
ENSLACG00000007235
Uncharacterized protein (230 aa)
     
   
  0.598
IRF2
Interferon regulatory factor 2 (342 aa)
     
0.595
ENSLACG00000000241
Uncharacterized protein (143 aa)
     
   
  0.572
CIITA
Class II, major histocompatibility complex, transactivator (793 aa)
     
 
  0.562
STAT5B
Signal transducer and activator of transcription (786 aa)
     
  0.562
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: Actinistia, Choanichthyes, Coelacanthidae, Coelacanthiformes, Coelacanthimorpha, Crossopterygii, L. chalumnae, Latimeria, Latimeria chalumnae, Latimeriidae, coelacanth, coelacanths, lobe-finned fishes
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