STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2ZWF8_LATCHLeucine-rich repeats and IQ motif containing 1. (1148 aa)    
Predicted Functional Partners:
ACVR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
  0.823
CCDC113
Coiled-coil domain containing 113.
   
 
 0.773
LOC102366597
SMC_N domain-containing protein.
   
   0.676
LOC102350363
Structural maintenance of chromosomes 2.
   
   0.676
EFHC1
EF-hand domain containing 1.
   
 
 0.658
FEM1B
Fem-1 homolog B.
    
 0.653
SYCE1
Uncharacterized protein.
      
 0.635
LOC102354290
Uncharacterized protein.
    
 0.634
SPACA1
Uncharacterized protein.
    
 
 0.618
SPAG17
Sperm associated antigen 17.
   
 
 0.611
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.