STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3YL1SH3 and SYLF domain containing 1. (341 aa)    
Predicted Functional Partners:
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
   0.848
TMEM53
Transmembrane protein 53.
      
 0.682
LOC102357229
WASP like actin nucleation promoting factor a.
    
 
 0.680
WAS
Uncharacterized protein.
    
 
 0.680
WASL
WASP like actin nucleation promoting factor.
    
 
 0.680
LOC102346266
Uncharacterized protein.
    
 
 0.680
H3A9K3_LATCH
Uncharacterized protein.
    
 
 0.634
LOC102346832
Si:dkey-280e21.3.
    
 
 0.634
SMAP2
Small ArfGAP2.
    
 
 0.609
NBR1
NBR1 autophagy cargo receptor.
   
  
 0.594
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.