Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3YL1SH3 and SYLF domain containing 1. (341 aa)    
Predicted Functional Partners:
SH3D19
SH3 domain containing 19.
    
   0.902
SH3D19-2
Uncharacterized protein.
    
   0.902
SMAP2
Small ArfGAP2.
    
 
 0.791
NTPCR
Nucleoside-triphosphatase, cancer-related.
      
 0.770
H2ZX25_LATCH
ANK_REP_REGION domain-containing protein.
    
 
 0.727
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
   0.726
FKBP8
Peptidylprolyl isomerase.
      
 0.707
AR
Androgen receptor.
    
 
 0.694
SMAP1
Small ArfGAP 1.
    
 
 0.668
PGR
Progesterone receptor.
    
 
 0.642
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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