Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102363644Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (262 aa)    
Predicted Functional Partners:
MAOB
Amine oxidase.
     
 0.962
PNMT
Phenylethanolamine N-methyltransferase.
     
 0.953
DDC
Dopa decarboxylase.
   
 
 0.952
LOC102362765
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
     
 0.948
DBH
Dopamine beta-hydroxylase.
     
 0.947
LOC102349352
Amine oxidase.
     
 0.938
LOC106703932
Amine oxidase.
     
 0.938
LOC102346260
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
    
 0.933
ALDH3B1
Aldehyde dehydrogenase 3 family, member B1; Belongs to the aldehyde dehydrogenase family.
   
 
 0.926
LOC102367556
Uncharacterized protein.
   
 
 0.919
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: high (92%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.