Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM12ADAM metallopeptidase domain 12. (389 aa)    
Predicted Functional Partners:
SH3PXD2A
SH3 and PX domains 2A.
    
 0.637
CDH1
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.601
HYAL4
Hyaluronidase.
   
 
 0.590
SPAM1
Hyaluronidase.
   
 
 0.590
LOC102349128
Hyaluronidase.
   
 
 0.590
H3BDW1_LATCH
Ion_trans domain-containing protein.
   
  
 0.584
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2.
      
 0.524
SH3PXD2B
SH3 and PX domains 2B.
    
 0.518
LGI3
Leucine rich repeat LGI family member 3.
     
 0.515
LGI2
Leucine rich repeat LGI family member 2.
     
 0.496
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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