Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKS3Ankyrin repeat and sterile alpha motif domain containing 3. (661 aa)    
Predicted Functional Partners:
ANKS6
Ankyrin repeat and sterile alpha motif domain containing 6.
    
 
 0.974
NEK7
NIMA related kinase 7; Belongs to the protein kinase superfamily.
    
 0.876
NEK6
NIMA related kinase 6; Belongs to the protein kinase superfamily.
    
 0.876
NEK8
NIMA related kinase 8.
    
 
 0.870
WDR90
WD repeat domain 90.
    
 0.800
RMND5A
Required for meiotic nuclear division 5 homolog A.
      
 0.790
WDR24
WD repeat domain 24.
   
 
 0.777
XPNPEP3
X-prolyl aminopeptidase 3.
    
 
 0.776
RHOT2
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
   
 0.754
RHBDL1
Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
      
 0.752
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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