Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANGPTL6Fibrinogen C-terminal domain-containing protein. (519 aa)    
Predicted Functional Partners:
DMAP1
DNA methyltransferase 1 associated protein 1.
      
 0.658
S1PR2
Sphingosine-1-phosphate receptor 2.
      
 0.552
SWSAP1
Uncharacterized protein.
      
 0.498
KANSL2
KAT8 regulatory NSL complex subunit 2.
    
 0.489
ATG7
Autophagy related 7.
     
 0.480
TEX30
Testis expressed 30.
    
 0.458
MCRS1
Microspherule protein 1.
    
 0.445
CDC37
Cell division cycle 37.
      
 0.428
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
   
  
 0.402
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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