Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2ZWQ9_LATCHWD_REPEATS_REGION domain-containing protein. (483 aa)    
Predicted Functional Partners:
H3ADV1_LATCH
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
    
 0.985
TIRAP
TIR domain containing adaptor protein.
    
   0.917
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.908
PARP4
Poly [ADP-ribose] polymerase.
   
 
 0.905
MVP
Major vault protein.
    
 
 0.875
TAF9
TATA-box binding protein associated factor 9.
   
 0.827
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.802
CDC73
Cell division cycle 73.
    
 0.798
WDR90
WD repeat domain 90.
   
 0.766
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.766
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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