STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYGSCrystallin gamma S; Belongs to the beta/gamma-crystallin family. (178 aa)    
Predicted Functional Partners:
CRYAA
Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.806
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
   
  
 0.699
CRYAB
Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.606
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
      
 0.582
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
   
 
0.579
KMO
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
      
 0.509
LAMB2
Laminin subunit beta 2.
      
 0.508
ACTR5
Actin related protein 5; Belongs to the actin family.
      
 0.507
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
      
 0.507
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
      
 0.502
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.