Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRYGSCrystallin gamma S; Belongs to the beta/gamma-crystallin family. (178 aa)    
Predicted Functional Partners:
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
      
 0.966
CRYAB
Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.935
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
   
  
 0.831
CRYAA
Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.823
NDUFAF4
NADH:ubiquinone oxidoreductase complex assembly factor 4.
    
   0.780
LOC102350341
Uncharacterized protein.
    
   0.687
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
   
 
 0.656
CRYBA4
Crystallin beta A4; Belongs to the beta/gamma-crystallin family.
   
  
 0.613
TBCCD1
TBCC domain containing 1.
 
    
 0.534
LOC102362258
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.534
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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