Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP1Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family. (739 aa)    
Predicted Functional Partners:
WDR48
WD repeat domain 48.
    
 0.999
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.996
FANCD2
FA complementation group D2.
    
 0.996
FANCI
FA complementation group I.
   
 0.993
FANCL
FA complementation group L.
     
 0.983
KLHDC2
Kelch domain containing 2.
    
 
 0.944
RPS27A
Ribosomal protein S27a.
    
  0.939
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
    
 
 0.927
KPNA1
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.906
ATAD5
ATPase family AAA domain containing 5.
   
 0.891
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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