STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (451 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.998
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.985
P4HB
Protein disulfide-isomerase.
  
0.979
PDIA3
Protein disulfide-isomerase.
   
 0.964
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.960
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.958
TXNDC5
Thioredoxin domain containing 5.
   
 
0.958
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
   
 0.950
ERP29
Endoplasmic reticulum protein 29.
   
 0.949
DDOST
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 
 0.945
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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