STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP3Insulin like growth factor binding protein 3. (288 aa)    
Predicted Functional Partners:
IGF1
Insulin like growth factor 1.
     
 0.923
IGF2
Insulin like growth factor 2.
   
 0.761
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
      
 0.586
FST
Follistatin.
      
 0.557
VSTM2L
V-set and transmembrane domain containing 2 like.
      
 0.509
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.505
SFRP2
Secreted frizzled related protein 2.
    
 
 0.467
DHX30
DExH-box helicase 30.
      
 0.437
IGFALS
Insulin like growth factor binding protein acid labile subunit.
    
 0.414
GHR
Growth hormone receptor.
      
 0.408
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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