Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TMX2Thioredoxin-related transmembrane protein 2a. (307 aa)    
Predicted Functional Partners:
NDRG3
NDRG family member 3.
   
   0.825
TMX4
Thioredoxin related transmembrane protein 4.
    
 
 0.821
TMX1
Thioredoxin related transmembrane protein 1.
    
 
 0.764
PITPNM1
Phosphatidylinositol transfer protein membrane associated 1.
      
 0.724
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
      
 0.679
B3GNT5
Hexosyltransferase.
      
 0.669
AK4
Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
      
 0.641
TAPBP
Uncharacterized protein.
      
 0.641
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
      
 0.641
CCDC39
Coiled-coil domain containing 39.
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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